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StockUnited StatesNasdaqGS

IONS

Ionis Pharmaceuticals, Inc.

Healthcare · Biotechnology

56.02USD

-0.6900 (-1.22%)

DescriptionHistoricalFinancialsRelative ValueResearchNewsDiscussionOptionsPrice Chart ↗Fundamental Chart ↗

Estimates and surprises

Consensus EPS on the street’s adjusted basis, not the filed GAAP figure — which is why the actuals here can differ from the income statement.

PeriodConsensus EPS90 days agoRevisions up (30d)Revisions down (30d)
Current quarter$-0.92▼$-0.8115
Next quarter$-0.89▼$-0.6205
Current year$-2.72▼$-2.5641
Next year$-1.08▼$-0.6242

Recent quarters

Beat in 4 of the last 4

QuarterEstimateActualSurprise
2026-06-30$-0.88$-0.42+0.45 (+51.7%)
2026-03-31$-0.78$-0.3+0.47 (+60.9%)
2025-12-31$-1.22$-1.15+0.07 (+5.6%)
2025-09-30$-1.05$-0.61+0.44 (+41.8%)

Wall Street coverage

267 ratings from 32 firms

Ratings are attributed to the research firm, not to individual analysts. See every ticker.

FirmActionRatingPrice TargetDate
Morgan StanleyMaintainedOverweight$110 $104Sep 8, 2026
Goldman SachsMaintainedNeutral$69 $56Sep 8, 2026
BMO CapitalMaintainedMarket Perform$61 $54Sep 8, 2026
Canaccord GenuityMaintainedBuy$95 $85Sep 8, 2026
HC Wainwright & Co.MaintainedBuy$115 $100Sep 8, 2026
NeedhamReiteratedBuy$86Sep 4, 2026
BMO CapitalMaintainedMarket Perform$60 $61Sep 4, 2026
HC Wainwright & Co.ReiteratedBuy$115Sep 4, 2026
HC Wainwright & Co.ReiteratedBuy$115Aug 31, 2026
BMO CapitalInitiated from OutperformMarket Perform$60Aug 19, 2026
JP MorganMaintainedOverweight$72 $76Aug 3, 2026
Wells FargoMaintainedOverweight$100 $95Jul 30, 2026
HC Wainwright & Co.MaintainedBuy$125 $115Jul 30, 2026
GuggenheimMaintainedBuy$106 $89Jul 21, 2026
Wolfe ResearchDowngraded from OutperformPeer Perform—Jul 16, 2026
RBC CapitalMaintainedOutperform$100 $85Jul 13, 2026
HC Wainwright & Co.MaintainedBuy$130 $125Jul 10, 2026
Morgan StanleyMaintainedOverweight$130 $110Jul 10, 2026
BarclaysMaintainedOverweight$115 $90Jul 10, 2026
Canaccord GenuityMaintainedBuy$110 $95Jul 10, 2026
CitigroupMaintainedBuy$115 $100Jul 10, 2026
JefferiesMaintainedBuy$113 $90Jul 9, 2026
NeedhamMaintainedBuy$105 $86Jul 9, 2026
Goldman SachsMaintainedNeutral$74 $75Jun 25, 2026
Leerink PartnersMaintainedOutperform$122 $129Jun 25, 2026

Insider transactions

154 filings from 24 insiders · 21 buy / 27 sell over 6m

Officers and directors of IONS, from the last two years of filings. Grants, gifts and option exercises are shown but not colour-coded — they are compensation, not a view on the price.

InsiderActionSharesPriceValueDate
BENNETT C FRANKOfficer, EVP, Chief Scientific OfficerOther110$51.31$6kAug 31, 2026
O'NEIL PATRICK R.Officer, EVP CLO & General CounselOther63$51.31$3kAug 31, 2026
Monia Brett PDirector; Officer, Chief Executive OfficerOther98$51.31$5kAug 31, 2026
Birchler BrianOfficer, EVP, Corp and Development OpsOther58$51.31$3kAug 31, 2026
HAYDEN MICHAEL REUBENDirectorBuyindirect20.0k$51.60$1.06MJul 31, 2026
BERTHELSEN SPENCER RDirectorOther5.2k——Jul 15, 2026
HERMAN JOAN EDirectorOther5.2k——Jul 15, 2026
DIAZ ALLENE M.DirectorExercise10.1k$47.11$476kJul 7, 2026
KORDASIEWICZ HOLLY BOfficerSell362$84.30$31kJul 7, 2026
DIAZ ALLENE M.DirectorSell10.1k$85.42$864kJul 7, 2026
BENNETT C FRANKOfficerSell20.5k$83.58$1.74MJul 7, 2026
KLEIN JOSEPH S IIIDirectorExercise11.5k$39.94$460kJul 1, 2026
KLEIN JOSEPH S IIIDirectorSell11.5k$79.04$910kJul 1, 2026
BAROLDI JOSEPHOfficerExerciseindirect5.6k$32.60$277kJun 26, 2026
SCHNEIDER EUGENEOfficerExercise26.0k$60.89$1.58MJun 26, 2026
MONIA BRETT PChief Executive OfficerExercise85.6k$32.60$4.00MJun 26, 2026
BAROLDI JOSEPHOfficerSellindirect5.6k$80.16$452kJun 26, 2026
SCHNEIDER EUGENEOfficerSell26.0k$81.05$2.11MJun 26, 2026
MONIA BRETT PChief Executive OfficerSell85.6k$78.41$6.83MJun 26, 2026
O'NEIL PATRICK RGeneral CounselSell3.1k$80.00$246kJun 26, 2026

Analyst Notes

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No analyst notes on IONS yet.

Analyst Ratings

22 analysts covering

PeriodStrong BuyBuyHoldSellStrong SellConsensus
Current910500Buy1.83
1 mo ago910500Buy1.83
2 mo ago910400Buy1.78
3 mo ago812400Buy1.83
Price target$88.14$61.00 – $115.00
+57.3% to target